If you mean harvesting tidal energy, the effect on the moon would be minimal. The loss of angular momentum the moon experiences is due to the mass of the earth’s waters. I could not imagine anything humans could build that could extract enough tidal energy that it would disrupt the moon without utterly destroying the environment at the same time (by way of nullifying tides somehow). In fact, to harness tidal energy, one way would be to use underwater turbines. They would have an immediate effect to the local environment but a negligible amount to the moon itself.

The opposite happens. Tidal energy is what causes the moon to drift farther away from the earth, as the moon loses angular velocity.